Medical Disclaimer
Last updated: July 25, 2026
MarkerScore is an educational longevity calculator. Before you use your score or share it with anyone, please read the following in full.
Please read before relying on this tool.
- This tool is for educational and informational purposes only. It is not medical advice, diagnosis, or treatment.
- It is not a medical device and has not been evaluated or approved by the FDA or any other regulatory body.
- Your score reflects statistical associations observed in population studies — it is not a prediction about you as an individual.
- The hazard ratios behind each metric come from observational cohort studies. Association is not causation.
- Never disregard, avoid, or delay professional medical advice because of something you read here.
- Do not use this tool to start, stop, or change any medication or treatment.
- If you are experiencing a medical emergency or urgent symptoms, call your local emergency number immediately.
- Results are only as accurate as the values you enter — self-reported inputs carry real measurement error.
How to interpret your score
50 is a typical person on all eight. The scale goes to 100; that is a cap, not a test score. Your score and percentile are a directional summary of how your entered metrics compare to published, population-level hazard ratios for all-cause mortality. A higher score means your inputs are associated, on average across large cohort studies, with lower relative risk than a defined median reference adult — it does not mean you personally will or will not experience any particular health outcome. Small changes in the score should not be over-interpreted; treat it as a rough compass for where to focus attention, not a diagnosis or a guarantee. For the full mechanics of how the score is built — including where curve shapes are directly from the literature versus interpolated — see Methodology & Sources.
Known limitations of the model
- The 8 inputs are correlated with one another in ways the model does not fully account for.
- The percentile comes from a 100,000-profile-per-sex simulation over published marginal distributions for each metric, not from measured population data, and it samples each metric independently, so it understates how spread out the real population actually is.
- Several curve shapes (grip strength, VO2 max) are our own construction based on the direction and rough magnitude reported in the source study, not a value lifted directly from a published table.
- Self-reported and home-measured inputs — blood pressure, grip strength, VO2 max, sleep — carry real measurement error depending on your equipment and technique.
- The model estimates relative, population-level mortality association. It does not model any specific disease, and it does not account for family history, genetics, current medications, or conditions you have not entered.
- Every user is scored against the same fixed ~45-year-old reference profile, regardless of the age you enter. Several underlying studies report that a marker's health association changes with age (for example, daily step count and resting heart rate), and that age-adjustment is not currently applied — your score reflects your distance from a 45-year-old reference, not from someone your own age.
See Methodology & Sources for the complete, current list of limitations and the primary study behind every metric.
Who should not rely on this tool
This calculator was built and validated against general adult population studies. It is not appropriate for, and should not be used by or relied upon for:
- Pregnant users — pregnancy substantially changes normal ranges for blood pressure, heart rate, weight, and other metrics used here, and none of the underlying studies were conducted on pregnant populations.
- Users under 18 — the reference cohorts and hazard ratios are derived from adult populations and do not apply to children or adolescents.
- People with a diagnosed chronic disease already managed by a clinician — for example diabetes, cardiovascular disease, chronic kidney disease, or cancer. Your treating clinician's guidance, informed by your full history and clinical exam, always takes precedence over a general population estimate.
This tool cannot detect or rule out any disease
MarkerScore does not screen, diagnose, detect, or rule out any medical condition. A high score does not mean you are free of disease, and a low score does not mean you have one. Only appropriate clinical evaluation by a qualified healthcare professional can do that. If you have any symptom that concerns you, or if you are due for routine screening, see a clinician — regardless of what your score shows.
Regulatory framing
MarkerScore is a general-wellness tool, not a medical device, and no FDA clearance, exemption, or determination has been sought or granted — this is our own compliance classification under FDA's General Wellness: Policy for Low Risk Devices guidance, not a government sign-off, and we say so plainly rather than implying otherwise. That guidance covers products either making no disease reference, or — our case, since some metrics like ApoB and HbA1c reference cardiovascular and metabolic risk — helping people pursue a well-documented, well-understood healthy-lifestyle association with a named condition, without diagnosing, treating, curing, or mitigating it. Every score here is an explicitly-labeled population-level hazard-ratio association, never an individual diagnosis or risk determination, and the UI unconditionally defers to a clinician (see "This tool cannot detect or rule out any disease" above). Under FTC guidance, every substantive claim is tied to its cited study, with weighting uncertainty published, not hidden (see Methodology & Sources) — no claim of a guaranteed outcome. Any future feature that screens for, diagnoses, or predicts a specific individual's disease status would require this section, and our regulatory posture, to be revisited before shipping.